Journal: Cancers
Article Title: c-Met and EPHA7 Receptor Tyrosine Kinases Are Related to Prognosis in Clear Cell Renal Cell Carcinoma: Focusing on the Association with Myoferlin Expression
doi: 10.3390/cancers14041095
Figure Lengend Snippet: Immunohistochemical (IHC) staining for EPHA7 in relation to myoferlin expression and prognosis in clear cell renal cell carcinoma. ( a ) The IHC staining level of EPHA7 was similar between myoferlin-high and myoferlin-low cancers, ( b ) high EPHA7 expression (score 8, strong expression in 67–100%), ( c ) low EPHA7 expression (score 2, weak expression in 0–1%), ( d ) progression-free survival, ( e ) overall survival, and ( f ) cancer-specific survival. Scale bar = 100 μm.
Article Snippet: The following RTKs and ligands were examined using IHC staining: c-Met (ready-to-use, SP44, Ventana, Tucson, AZ, USA), Eph receptor A7 (EPHA7; 1:800, 6C8G7, Novus Biologicals, Centennial, CO, USA), HER2 (ready-to-use, 4B5, Ventana), hepatocyte growth factor (HGF; 1:100, ab118871, Abcam, Cambridge, UK), VEGFA (1:300, sc-7261, Santa Cruz Biotechnology, Dallas, TX, USA), and ephrin A5 (EFNA5; 1:100, LS-C356004, Lifespan Biosciences, Seattle, WA, USA).
Techniques: Immunohistochemical staining, Immunohistochemistry, Expressing